Gene expression profiling of hairy cell leukemia reveals a phenotype related to memory B cells with altered expression of chemokine and adhesion receptors

Basso, K., Liso, A., Tiacci, E., Benedetti, R., Pulsoni, A., Foa, R., Di Raimondo, F., Ambrosetti, A., Califano, A., Klein, U., Dalla-Favera, R., Falini, B.

J. Exp. Med. 199 (1): 59-68

This website contains the primary Affymetrix U95A gene chip hybridization data used in the above analysis in two forms:

1.)    Affymetrix CEL files.

For the .CEL files corresponding to:

·        Normal B cells see Klein, U., et al Proc. Acad. Natl. Sci. U.S.A. 100:2639-2644 (2003);

·        BL, FL, DLBCL, B-CLL see Klein, U., et al. J. Exp. Med. 97: 2098-2104 (2001);

·        LCL and MM cell lines see Klein, U., et al. Blood 101(10): 4115-4121 (2003).

2.)    The “average differences”/“signals” and the A, M or P calls of the respective samples as obtained by analyzing CEL files using Microarray Suite (MAS) 5.0 with standard parameters and TGT=2,500. The respective “signals” of the probe sets are ordered as in the Affymetrix CHP file. Of note, the “spike control” probe set values are omitted.

It also contains the supplemental Tables 1, 2, 3 and 4 and the supplemental Materials and Methods.

Source	Format	Size	Download
HCL .CEL	ZIP	47 MB
MCL .CEL	ZIP	33 MB
All Data in Excel	ZIP	10 MB

The decompression program is available at http://www.winzip.com