Dr. Richard Baer

Dr. Richard Baer

Biography
Research Summary
Publications
Lab Members

Richard Baer Ph.D.

Professor of Pathology & Cell Biology

Ph.D. Rutgers College, New Brunswick, New Jersey

Location:  ICRC 503A  
Phone: 212-851-5275
Email: rb670@columbia.edu

 

I am a Professor of Pathology & Cell Biology at Columbia University Medical Center (CUMC), the Deputy Director of the CUMC Institute for Cancer Genetics, and the Associate Director for Basic Science of the CUMC Herbert Irving Comprehensive Cancer Center.  Since 1987, I have maintained an independent program of cancer research that has been supported continuously by R01/P01 grants from the NCI.  My independent work was initially focused on the discovery and characterization of TAL1 and TAL2, proto-oncogenes that are malignantly activated in approximately half of patients with T cell acute lymphoblastic leukemia.  For the past 15 years, I have studied the role of the BRCA1 tumor suppressor in hereditary breast cancer.  In the course of this work, our laboratory discovered the BARD1 protein and showed that the biochemical, developmental, and tumor suppression functions of BRCA1 are mediated primarily by the BRCA1/BARD1 heterodimer.  We also identified CtIP as a major interacting partner of BRCA1 and, in collaborative studies, demonstrated the requirements for CtIP in DNA resection, homology-directed repair of DNA double-strand breaks, and cell cycle checkpoint control.  

Positions

1981 - 1987: Postdoctoral Fellow; MRC-Laboratory of Molecular Biology, Cambridge, UK

1987 - 1990: Assistant Professor of Microbiology; U.T. Southwestern Medical Center

1990 - 1995: Associate Professor of Microbiology; U.T. Southwestern Medical Center

1995 - 1999: Professor of Microbiology; U.T. Southwestern Medical Center, Dallas, TX

1999 - present: Professor of Pathology & Cell Biology; Columbia University Medical Center (CUMC)

2005 - present: Assoc. Director for Basic Research; CUMC Herbert Irving Comprehensive Cancer Center 

2007 - present: Deputy Director; CUMC Institute for Cancer Genetics

Honors

1981 - 1982: Postdoctoral Fellowship; Damon Runyon/Walter Winchell Cancer Fund

1983 - 1985: Postdoctoral Fellowship; Lady Tata Memorial Trust

1990 - 1992: Junior Faculty Research Award; American Cancer Society

1993 - 1997: Faculty Research Award; American Cancer Society