Gene Expression Profiling of B-cell Chronic Lymphocytic Leukemia Reveals a Homogeneous Phenotype Related to Memory B Cells

 

Klein, U., Y. Tu, G.A. Stolovitzky, M. Mattioli, G. Cattoretti, H. Husson, A. Freedman, G. Inghirami, L. Cro, L. Baldini, A. Neri, A. Califano, and R. Dalla-Favera.

 

J. Exp. Med. 194:1625-1638, 2001

 

 

This website contains the primary Affymetrix U95A gene chip hybridization data used in the above analysis in two forms:

 

1.) Affymetrix CEL files obtained after scanning with the original PMT (photomultiplier tube) settings. See below, ordered according to categories.

 

2.)    The “average differences” /“signals” and the A, M or P calls of the respective samples as obtained by analyzing CEL files using Microsoft Analysis Suite (MAS) 5.0 with standard parameters and TGT=2,500. See below: “All Data – EXCEL table”. Of note, the “average differences” used for the analysis described in the present manuscript were obtained with MAS4.0 (TGT=2,500); we here chose to deposit primary data analyzed with MAS5.0 to allow future comparisons. The respective “signals” of the probe sets are ordered as in the Affymetrix CHP file; of note, the “spike control” probe set values are omitted.

 

Source

Format

Size

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Normal B-cell Subsets

ZIP

67 MB

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BL

ZIP

40 MB

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B-CLL

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106 MB

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DLCL

ZIP

46 MB

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FL

ZIP

20 MB

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Cord Blood

ZIP

17 MB

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All Data - EXCEL table

ZIP

10 MB

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The decompression program is available at http://www.winzip.com